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Celebs and their career-ending interviews: From Charlie Sheen's TV bombshell to John Mayer's degrading comments about Jessica Simpson - the most infamous car crash conversations

Celebs and their career-ending interviews: From Charlie Sheen's TV bombshell to John Mayer's degrading comments about Jessica Simpson - the most infamous car crash conversations

Just as an interview can send a celeb's star power soaring, an ill-thought out comment can destroy careers.

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