Male bias in medical trials risks women’s lives. But at least the data gap is finally being addressed | Caroline Criado Perez

We know some medications work differently in men and women. Why is it taking so long for studies to reflect this?The first step, they say, is admitting you have a problem, and on that front the UK’s Medicines and Healthcare products Regulatory Agency (MHRA) has made some much-needed progress. The agency, which is responsible for approving all clinical trials in the UK, has identified a “notable imbalance” in trials conducted between 2019 and 2023: there were nearly twice as many all-male trials as all-female trials.This imbalance is hardly surprising: as I documented in Invisible Women, my book on the female data gap, the failure to adequately represent women in clinical trials is a longstanding and global problem. The MHRA’s figures are also in line with a recent US analysis that found male-prevalent diseases receive nearly twice as much funding as female-prevalent diseases, both absolutely and relative to disease burden. So far, so disappointingly standard.Caroline Criado Perez is the author of Invisible Women: Exposing Data Bias in a World Designed for MenDo you have an opinion on the issues raised in this article? If you would like to submit a response of up to 300 words by email to be considered for publication in our letters section, please click here. Continue reading...

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